Disorder of Sex Development defined as congenital conditions in which the development
of chromosomal, gonadal, or anatomic sex is atypical. In Islam, gender decision of khunsa
is difficult since it still relies on the traditional approach of observing how people urinate
and observing the physical features that emerge, whereas gender identity must be
determined early because it affects every day worship activities. The goal of this research
is to use a medical method to examine the renewal of khunsa gender determination in
Islam. The descriptive qualitative analysis method is used in this study. The findings of this
study suggest that in Islam, determining khunsa gender through a medical approach is
warranty. In Islam, the importance of gender identity is particularly significant in issues
of worship, such as congregational prayers, inheritance, aurat limitations, and marriage.
Understanding and adjustment of medical diagnosis issues, community culture, and
religious law need to be synchronized to improve the quality of life for people with gender
ambiguity that do not deviate from religious principles and can be accepted in society
without discrimination. To the best of our knowledge this is the first study of combine
Islamic law and modern medicine