The study aims to know the degree of academic and administrative leadership practice knowledge management at Al Al-Bayt University in the Hashemite Kingdom of Jordan, and the effect of variables (gender, educational qualification, years of experience, stage, and job title) on that. The study sample consists of (375) faculty and administrative members. To achieve the goals of the study, a tool was built to measure the degree of knowledge management practice, which consists of (37) items distributed into four areas, namely (knowledge organization, knowledge generation, knowledge sharing, and application of knowledge). Validity and reliability were verified, and the descriptive survey method was used. The results of the study show that the degree of academic and administrative leaders' practice of knowledge management at Al Al-Bayt University in the Hashemite Kingdom of Jordan, from the viewpoint of their colleagues, came with a medium degree in all fields. The results also show that there were statistically significant differences between the averages of the responses of the study sample individuals due to the gender variable, and the differences are in favor of males in all fields. The results also show that there are statistically significant differences attributable to the variable of the academic qualification in the fields of sharing and applying knowledge, and the differences are in favor of the qualification of (Bachelor). The presence of statistically significant differences attributable to the variable of years of experience in the areas of knowledge sharing and application; the absence of statistically significant differences is attributable to the job title in all fields. In light of the results, the study presents a set of recommendations, the most important of which are training academic and administrative leaders on the application of knowledge management; training academic staff on teaching and evaluation methods that help to raise the levels of performance in the educational learning process.